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Best For: Just starting a natural Lyme protocol, Borrelia burgdorferi, Babesia co-infection, biofilm and persister cell support, neurological Lyme symptoms, brain fog, joint pain, anyone who has tried antibiotics without full resolution, those researching the Buhner protocol for the first time, treatment-resistant Lyme
Who Can Use It: 12+ with practitioner guidance / Adults 18+
Suggested Use:
Adults (18+):
- Japanese Knotweed: 0.5–1 mL, 3x daily
- Cryptolepis: 0.5–1 mL, 3x daily
Adolescents Dosing (12–17 years) — under practitioner guidance:
- Japanese Knotweed:
- 12–13 years: 0.2–0.3 mL, 2x daily
- 14–15 years: 0.3–0.5 mL, 2x daily
- 16–17 years: 0.4–0.6 mL, 2x daily
- Cryptolepis:
- 12–13 years: 0.25–0.4 mL, 2x daily
- 14–15 years: 0.3–0.5 mL, 2x daily
- 16–17 years: 0.4–0.6 mL, 2x daily
Not recommended under 12 years of age.
When To Take It: With meals — spread doses throughout the day for consistent support
Start Feeling It: Commit to at least 60–90 days of consistent use for meaningful results
⚠️ Not recommended under 12. Adolescent use should be supervised by a qualified herbalist or healthcare provider. Consult your healthcare provider before use if taking prescription medications.
Japanese Knotweed is the cornerstone of nearly every natural Lyme protocol for good reason. Rich in resveratrol and powerful anti-inflammatory compounds, it crosses the blood-brain barrier to address neurological symptoms, directly targets Borrelia burgdorferi, and protects the joints, tissues, and cellular structures that Lyme systematically attacks. If you could only choose one herb for Lyme, most practitioners would point you here.
Cryptolepis handles what most antimicrobials simply can't reach. Borrelia is notorious for forming biofilms — protective shields that guard the bacteria from both the immune system and conventional antimicrobials. Cryptolepis is one of the few herbs with demonstrated ability to penetrate these biofilms and reach the persister cells hiding inside. It is also the most important herbal support for Babesia, a parasitic co-infection carried by the same ticks that transmit Lyme and one that is frequently missed despite causing profound fatigue, night sweats, and chills.
Together these two herbs cover the widest possible ground — active infection, biofilm, neurological protection, and co-infection support — in a simple, accessible two-bottle protocol.
For deeper and more comprehensive protocol coverage, consider upgrading to our Full Lyme Protocol Bundle — all four core herbs for just $20 more
Best For: Just starting a natural Lyme protocol, Borrelia burgdorferi, Babesia co-infection, biofilm and persister cell support, neurological Lyme symptoms, brain fog, joint pain, anyone who has tried antibiotics without full resolution, those researching the Buhner protocol for the first time, treatment-resistant Lyme
Who Can Use It: 12+ with practitioner guidance / Adults 18+
Suggested Use:
Adults (18+):
- Japanese Knotweed: 0.5–1 mL, 3x daily
- Cryptolepis: 0.5–1 mL, 3x daily
Adolescents Dosing (12–17 years) — under practitioner guidance:
- Japanese Knotweed:
- 12–13 years: 0.2–0.3 mL, 2x daily
- 14–15 years: 0.3–0.5 mL, 2x daily
- 16–17 years: 0.4–0.6 mL, 2x daily
- Cryptolepis:
- 12–13 years: 0.25–0.4 mL, 2x daily
- 14–15 years: 0.3–0.5 mL, 2x daily
- 16–17 years: 0.4–0.6 mL, 2x daily
Not recommended under 12 years of age.
When To Take It: With meals — spread doses throughout the day for consistent support
Start Feeling It: Commit to at least 60–90 days of consistent use for meaningful results
⚠️ Not recommended under 12. Adolescent use should be supervised by a qualified herbalist or healthcare provider. Consult your healthcare provider before use if taking prescription medications.
Japanese Knotweed is the cornerstone of nearly every natural Lyme protocol for good reason. Rich in resveratrol and powerful anti-inflammatory compounds, it crosses the blood-brain barrier to address neurological symptoms, directly targets Borrelia burgdorferi, and protects the joints, tissues, and cellular structures that Lyme systematically attacks. If you could only choose one herb for Lyme, most practitioners would point you here.
Cryptolepis handles what most antimicrobials simply can't reach. Borrelia is notorious for forming biofilms — protective shields that guard the bacteria from both the immune system and conventional antimicrobials. Cryptolepis is one of the few herbs with demonstrated ability to penetrate these biofilms and reach the persister cells hiding inside. It is also the most important herbal support for Babesia, a parasitic co-infection carried by the same ticks that transmit Lyme and one that is frequently missed despite causing profound fatigue, night sweats, and chills.
Together these two herbs cover the widest possible ground — active infection, biofilm, neurological protection, and co-infection support — in a simple, accessible two-bottle protocol.
For deeper and more comprehensive protocol coverage, consider upgrading to our Full Lyme Protocol Bundle — all four core herbs for just $20 more